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Severe Acute Respiratory Syndrome-Corona Virus 2 (SARS-CoV-2) or Corona Virus Disease 19 (COVID-19) is playing havoc all over the world since December 2019. Despite being a family member of coronaviridae, which has previously affected mankind twice in last one decade, the novel corona virus, as it is named left medical practitioners and scientists defenseless. The major challenge is twofold identification and therapeutic intervention. Several approaches, including real-time PCR have already...
Topics: SARS-CoV-2, Covid 19, Diagnostics, Therapeutic interventions, Real time PCR, Vaccine
The alarming multiple drug resistance developed by Escherichia coli towards the routine conventional antibiotics owing to their non-judicious usage is fast becoming a tough menace. This necessitates the urgent unleashing of novel and diverse strategies and antibacterial compounds. Since finding a new antibiotic from the scratch, followed by endless clinical trials is exceedingly time-consuming, a powerful alternate strategy of CADD coupled with repurposing the available drugs could save...
Topics: ESBL, Escherichia coli, Antibiotics, Anti-microbial resistance, Docking, Drug repurposing, DNA...
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There has been an increasing interest in remdesivir research within the scientific medical community because of the emerging evidence suggesting its beneficial role in patients with COVID‑19. Remdesivir which can be given intravenously and not orally has an anti-viral against several RNA viruses. Remdesivir has an in vitro antiviral activity against filoviruses, arenaviruses, and coronaviruses including circulating human coronaviruses HCoV-OC43, HCoV-229E, SARS, and MERS zoonotic...
Topics: Remdesivir, Emerging Evidence
The COVID-19 pandemic was an extreme situation that had a traumatic impact on psychosocial groups that performed their official duties in contact with the infected and sick, including in the gender aspect. Police officers were widely involved in anti-epidemic measures to protect order and citizens safety during the COVID-19 pandemic. The aim of the study is to identify the emotional reactions features in female police officers - the Moscow police employees, carrying serving as public order...
Topics: COVID-19, Female police officers, Mental health, Psychological trauma
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Feb 24, 2022 Journal of Biomedical Research & Environmental Sciences
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SARS-CoV-2 is the third most highly virulent human coronavirus of the 21st century. It is linked with fatal respiratory illness. Currently, there are still no effective treatments of Covid-19. Among many drugs evaluated, few have proven conclusive clinical efficacy. Furthermore, the spread of the disease mandates that ideal medications against Covid-19 be cheap and available worldwide. Therefore, there is a rationale to evaluate whether treatments of natural origin from aromatic and medicinal...
Topics: 3CL Protease, SARS-COV2, Gossypetin-3’-O-glucoside, Molecular docking, Free binding energy,...
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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The unique structures and properties of nanomaterials have attracted many engineers and scientists to these resources for different applications, including biomedical, electronics, manufacturing, transportation, energy, and defense. The increasing applications of nanomaterials have also caused some concern among the scientific community about their safety and cytotoxicity. To successfully use nanomaterials in different fields, their interaction with mammalian cells in vitro must be addressed...
Topics: Common nanomaterials, L929 and 3T3 cells, Cytotoxicity, Cell viability
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Misadventure of the Gastrostomy Tube (GT) has been described in the literature resulting in complications [1]. Here we present a case of dislodged GT diagnosed by contrast administration. The infant underwent GT placement for nutritional support. On the third post-operative day, she was started on Pedialyte solution five ml every three hours. Soon after the second feed, the infant was reported by the nurse to be agitated despite adequate sedation and pain management. Abdominal examination at...
Topics: x-ray fi lm showing, free air
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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At the end of 2019, a new coronavirus pneumonia turned into an epidemic in China and then spread to other countries around the world. This disease was identified as the COVID-19 (SARS-CoV-2) disease. SARS-CoV-2 RNA is detected by Reverse-Transcription Polymerase Chain Reaction (RT-PCR). A positive test for SARS-CoV-2 may confirm the diagnosis of COVID-19, but the results of false negativity and false positivity can be confusing. This article describes the negative COVID-19 RNA RT-PCR test...
Topics: COVID-19, Coronavirus, Polymerase chain reaction, Chemotherapy, Cancer
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Viruses are at the threshold of living and nonliving entities. Virus particles exhibit life-activities when are within their respective hosts and act as non-living when present outside their hosts. This feature is very interesting and the related investigations can help to understand the differences between the functionalities at bionanointerfaces under living and nonliving phases. Metal and metal oxide nanomaterials occur naturally and are synthesized as per the need to meet the set targets....
Topics: Bionanointerface, Metal and metal oxide nanoparticles, Virus, Surface of a virus, Uptake of virus...
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Misadventure of the chest tube has been described in the literature resulting in complications [1-5]. Here we present a case of right pneumothorax in a preterm infant (Figure 1A). The pneumothorax was appropriately treated with a right pigtail inserted using the Seldinger technique (Figure 1B). However, on the follow up chest x-ray, the chest tube as noted to be lying outside the chest wall (Figure 1C). On careful inspection, we noted that infant has kicked the chest tube out (Figure 2). Infant...
Topic: Chest x-ray
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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This report was based on the comparative study on effectiveness of adsorption of food colors using coconuts and groundnut shell. The activated carbon (coconuts and groundnut shells) were cut into pieces in a furnace at a temperature of 450°C then crushed and sieved using different mesh sizes and activated using hydrochloric acid of different concentration. The food colors (sunset yellow and tartrazine) was prepared with different concentration and calibration curve was drawn, and the required...
Topics: Sunset yellow, Tartraxine, Groundnut shell, Coconut shell, Adsorption, Isotherm
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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A new type of pneumonia had developed from Wuhan Province in China in December 2019, caused by a novel member of the Coronaviridae family named Severe Acute Respiratory Coronavirus 2 Syndrome (SARS-CoV-2) . The disease is characterized by fatigue, dry cough, fever, and dyspnea . In a more severe case, the picture may become more complicated by the onset of interstitial pneumonia with alveolar damage, which clinically can lead to severe Acute Respiratory Distress Syndrome (ARDS) and even death ....
Topic: COVID-19 Pandemic
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Introduction: Acute Respiratory Distress Syndrome (ARDS) is a common finding among pediatric and adult patient populations . ARDS-related mortality remains high and is associated with prolonged hospital Length of Stay (LOS) and multiple ventilator days. Studies have sought to predict whether certain risk factors can be associated with ARDS development and mortality. It remains to be established whether a strong association exists between ARDS patient demographic characteristics, hospital LOS...
Topics: ARDS, ARDS incidence, ARDS-related demographics, ARDS-related mortality
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Violence towards healthcare personnel in hospitals is a widespread worrying phenomenon, and it is considered a mirror to violence in society in general  There are many factors may share in this phenomenon as work overload, waiting times, and nurse-patient relations, responsibilities, environmental factors and patient-related factors.
Topic: COVID-19
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Myiasis, the invasion of tissues of live humans and vertebrate animals with dipteran larvae is common throughout the tropical regions of the world. It is a real welfare problem of worldwide distribution and a matter of great concern among medical and veterinary fields. The reports indicate that dogs are the most common canine species affected by myiasis. The present study was conducted to ascertain prevalence of myiasis among pet dogs and to identify myiasis-causing flies in India. The study...
Topics: Myiasis, Pet dogs, Dipteran larva, Parasitosis
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Ginger can be an important complementary medicine for prevention and treatment of different types of cancers, owing to its natural origin, safety, and low cost relative to synthetic cancer drugs. Ginger contains volatile oils, anthocyanins, tannins, phenolic compounds and sesquiterpenes anticancer effects of ginger may arise from the ability to induce changes in a number of cellular processes, including cell division, apoptosis and differentiation. In this study, anticancer activity of ginger...
Topics: Anticancer, Ginger, Zingiber officinale, 6-gingerol, Shogaol
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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A Linguistic Analysis using a Computer Program (LIWC) for the 58 entries over the last year of life of a young woman who died by suicide revealed 3 significant changes and 5 trends over time. In particular, the woman showed more anger as her death grew closer, and she focused less on the future. These results differ from those obtained from other studies of diaries, suggesting the importance of a psychological typology for suicides.
Topics: Suicidology, Mental health, Psychology
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Acceleration of worldwide infection with mutant of coronavirus SARS CoV-19 require new paradigmatic of human activity based on negative feed-back system following basic mechanism of Homeostasis of all living organisms and ecosystems. Condition of efficient primary prevention is better integration of cooperation of interdisciplinary teams of experts, knowledge-based society and decision-makers on local scale with working global network focused on common action for efficient protection against...
Topics: COVID-19, Biosphere, Immune suppressors
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Street food is food obtained from a street side vendor, often from a makeshift or portable stall and it feeds millions of people daily with a wide variety of foods that are relatively cheap and easily accessible. Street food is intimately connected with take-out, junk food, snacks, and fast foods but it is not protected against insects, dust etc; which may harbor foodborne pathogens. Pathogens present in street vended foods come from different sources and practices, such as, improper food...
Topics: Street food, Pathogen, Safety, Food borne illnesses, Ethiopia
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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The topic indicated in this mini-review is an essential factor for the improvement of society through a clean environment movement. Now, this era of microbes forces us to make such kind of development for creating hazard free and healthy life. Girls in rural areas use old cloths, tissue paper, cotton, wool pieces, or a combination of these items to manage menstrual bleeding. Qualitative studies indicate that only those girls who know about several conventional sanitary pads, they prefer to use...
Topics: Sanitary napkins, Biodegradable, Natural fiber, Bamboo-banana-jute- hemp fiber, Commercial,...
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The aim of this paper is to determine and discuss the Concentrations of Copper (Cu) in the different soft tissues of Perna viridis and surface sediments collected from western and eastern parts of Johore Singapore Causeway. In general, it is found that the different tissues of eastern mussel populations were found to have significant (p < 0.05) higher Cu levels than those in the western mussel populations. This indicated higher Cu bioavailability in the eastern part of causeway than that...
Topics: Different tissues, Metal distribution, Mussels Sediment
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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The finding of electron leakage during the electron transport within the mitochondrial membrane (in eukaryotes) or in the cell membrane of the prokaryotes is an important issue for the accumulation of the Reactive Oxygen Species (ROS) in the cytosol which in turn induce the probable aging of cells. In eukaryotes, mitochondrion is known to be the major site of the ROS generation in different pathological processes which may further cause cell damages as evident through the ischemia-reperfusion...
Topics: Electron transport, Reactive Oxygen Species (ROS) Electron/proton leakage, Mitochondrion
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Environmental Genomics serves as a guide for an environmental scientist who wishes to squeeze genomics to solve environmental problems. Environmental genomics try to find out the approach of an organism or group of organisms to the changes in their external environment at the genetic level [1]. Since the genome responses are diverse, environmental genomics has the necessity to integrate molecular biology, physiology, toxicology, ecology, systems biology, epidemiology and population genetics...
Topics: Environmental, Genomics Research
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Epilepsy is a rigorous transmission of electrical impulses across neurons of the brain and reported more prevalent in lower-income countries. A systematic literature review has been performed to implicate the impact of environmental variables on the occurrence of epilepsy using the following keywords: Epilepsy or environmental risk factors or seizures. More than 500 genes have been reported to involve in epilepsy potentially. Moreover, family history with neurological disorders, sleep apnea,...
Topics: Epilepsy, Seizures, Environmental factors
Community Data
Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Malaria is caused by four plasmodium species in humans (P. falciparum, P. vivax, P. malariae and P. ovale) which spread from one person to another via the bite of female Anopheles mosquito. P. falciparum causes most deaths from malaria [1] and is most prevalent on the African continent whereas P. vivax has a wider geographical distribution [2]. According to the latest WHO estimates, released in December 2015, there were 214 million cases of malaria in 2015 and 438,000 deaths [3]. Existing...
Topics: Artimisnine, K13, Malaria vaccine, RTS, AS01
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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The 2019 Novel Coronavirus (2019-nCoV) outbreak affected a large number of deaths with millions of confirmed cases worldwide. Coronavirus Disease (COVID-19) is associated with respiratory illness that lead to severe pneumonia and Acute Respiratory Distress Syndrome (ARDS). Although related to the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), Covid-19 shows some unique pathogenetic, epidemiological and clinical features. On the basis of the...
Topics: Middle East respiratory syndrome, Pathophysiology, Covid19, Betacoronavirus, Severe acute...
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Finding of vegetal species suitable for ecologic restoration in arid climates is a primary goal of most of the governmental and private companies for fighting against the desertification and the recovery of contaminated soils. The Prosopis genus, a desert woody leguminous, with a wide distribution around the world, represents a very interesting source of highly tolerant and adaptable trees for revegetation and bioremediation of soils contaminated with metal and metalloids (metal(loid)s). The...
Topics: Phytostabilization, NRAMP metal transporter, Fluorescence Rx quantification, Gene expression,...
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Organisms inhabiting in water require little amount of trace elements. At finest level they are favorable and further than that edge it affected the ecosystem. Continuous dumping of impurities like heavy metals from various supplies in significant quantities are constantly discharged into the rivers reaches estuaries and oceans. For the reason of this unwanted human liberation oceanic biosphere is recognized to hold heaviness of heavy metals. For most of the heavy metals estuarine sediments...
Topics: Trace elements, Heavy metals, Copper, Nickel, Zinc, Lead, Manganese
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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We suppose a hypothetical role of erythrocytes in COVID-19: Involvement of bone marrow; evidences of the presence of ferritins in the autoptic spleen; role of erythrocytes in the production of thrombosis; the reason of using chloroquine and heparin; the similar actions with HIV-1; protection of HIV patients and Thalassemic patients from Covid19; reason of increase of Kawasaki patients; At last the protective role of Methylene blue in COVID-19.
Topics: Covid19, Red blood cell, Methemoglobinemia, Methylene, blue Spleen, Thalassemia, HIV-1 Kawasaki...
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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This study was aimed at investigating the Antibiogram pattern of Potential Pathogenic Bacteria that are associated with Domestic dog faecal matter in Port Harcourt Metropolis. Convenient sampling techniques were explored for sample collection. A total of fifty samples were collected from domestic dogs from different locations (Agip estates, Rumuokoro, GRA, Sandfill, Town, RSU lecturers’ quarters) within Port Harcourt metropolis, Rivers State, Nigeria. The bacteriological analysis was...
Topics: Antibiogram pattern, Potential pathogenic bacteria, Domestic dog, Faecal matter, Zoonosis Resistant...
There are several viruses that are not currently covered by efficient antiviral terapies, as towards Poliovirus and the new Covid19. The spread of atypical viral strains strongly raises the need of having efficient terapies with wide coverage against viruses. In the following experiments it was used a composition comprising Glutathione Reductase (GSSG-r) and Oxidized Glutathione (GSSG), which we call GR compound, for pharmaceutical use as antiviral, in vitro, towards RNA nad DNA virus, and in...
Topics: Antiviral technology, (GSSG-r+GSSG), Cell membrane permeability, Viral proteins disulfide bridges
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Cinnamon is used in a variety of cuisines, herbal supplements, teas, and other unique variations. Use of it as a spice dates back thousands of years and is primarily found in the lower regions of Asia in places like Sri Lanka and India. This experiment was designed to examine the effects of cinnamon on visual motor reflexes. It was hypothesized that the longer a participant smelt cinnamon the faster their reflex time would be. Participants were used as an internal control to check their base...
Topics: Cinnamon herbal supplements, Spice, Visual motor reflexes, Smell of cinnamon, Antioxidants, Neural...
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Since December 2019, the outbreak of SARS-CoV-2 in WuHan, HuBei province, has spread to the whole country and abroad. As a susceptible population, the number of children and adolescents is increasing day by day. Under the severe situation of epidemic prevention and control, pediatric department has successively launched the expert consensus and treatment recommendations on the prevention and control of novel coronavirus pneumonia (COVID-19) in related fi elds. Syncope is a common emergency in...
Topics: COVID-19, Syncope, Rehabilitation, Children, Adolescents
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Microalgae are capable of absorbing and concentrating constituent elements that have a wide variety of applications in agriculture, food industry, and medicine. Microalgae chemical composition change according to internal and external factors. In this study, the effect of irradiance, sodium nitrate and sodium acetate concentration on the accumulation of essential minerals in Scenedesmus obliquus biomass were evaluated using 23 factorial screening designs. The simultaneous effect of the three...
Topics: Irradiance, Mineral, Scenedesmus obliquus, Sodium acetat, Sodium nitrate
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Introduction: Dermoid cysts are benign tumors that originate from aberrant primordial tissues. About 7% of all dermoid cysts are located in the head and neck region. We present here the case of a periorbital dermoid cyst in a 34 years old patient, involving the frontal bone. Case Report: We report the case of a 34 years old female patient, who has a history of a cystic formation of the superior inner angle of the right orbit, for which she received surgery 3 years prior. Clinical examination...
Topics: Dermoid cyst, Frontal bone, Frontal sinus
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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Introduction: Coronavirus Disease 2019 (COVID-19) originating from Wuhan, China, is spreading around the world. Apart from respiratory, cardiac and vascular complications, acute neurological symptoms and acute cerebrovascular disease have also been observed. Methods: A 36 year old female with severe cerebral stroke and COVID pneumonia and its clinical characteristics and evolution are described. Results of two retrospective studies about the incidence of Cerebrovascular Disease (CVD) amongst...
Topics: COVID-19, Infection, Stroke, Ischemia
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Jan 9, 2021 Journal of Biomedical Research & Environmental Sciences
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In a recent viewpoint publication in the Journal of American Medical Association (JAMA), Onder, et al. provided insight into the coronavirus disease 2019 (COVID-19) outbreak in Italy along with an explanation of the Italian National Institute of Health (Istituto Superiore di Sanita [ISS]) surveillance system [1]. Onder calculated the overall attributed COVID-19 fatality rate of 7.2% in the Italian population, based on the data up to March 17th, 2020 (1625 deaths/22 512 cases) [1]. Onder and...
Topics: Coronavirus, COVID19, Epidemy, Mortality, Estimate, Italy, Case fatality rate